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Image Search Results
Journal: Frontiers in Cell and Developmental Biology
Article Title: Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis
doi: 10.3389/fcell.2022.827714
Figure Lengend Snippet: Effects of A 2A inhibition on cerulein—induced inflammation, necroptosis and ER stress in AR42J cells. AR42J cells was pretreated with ABT702 or ZM241385 + ABT702 and then was exposed to cerulein for 24 h. (A) , NF-κB-P65 and the phosphorylation of NF-κB-P65 were immunoblotted. ( n = 5). (B) , The critical molecules of the necroptotic pathway were immunoblotted. ( n = 5). (C) , GRP78, PERK, p-PERK, eIF-2 α and p-eIF-2 α were immunoblotted. ( n = 5).
Article Snippet:
Techniques: Inhibition, Phospho-proteomics